Splenic Neutropenia in Felty's Syndrome

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Splenic neutropenia in the Felty syndrome.

By H. E. HUTCHISON AND W. D. ALEXANDER T HE POSSIBILITY that overactivity of the spleen might cause neutropemsia, mentiomsed by Bauer us 1899,’ was discussed at lemsgth by Framskm who drew attentious to the close associatious betweeus splemsomegaly of diverse etiology amid iseutropemsia; that was its 1916, the year its which Kaztselsonm first reported rise of the platelet coumit followiusg remo...

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Case report The patient was first seen at the age of 15 years in 1968 when the problem was one of severe oral ulceration of one year's duration. At that time he also had anterior uveitis. There was a marked neutropenia of less than 100 x 109/1. Because of severe symptoms, he was started empirically on a course of prednisolone with initial improvement. Subsequently, he had transient joint pains,...

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Neutropenia is a rare complication of Diamond-Blackfan syndrome (congenital hypoplastic anaemia). Three patients are reported: all had neutropenia as well as anaemia, and to investigate the cause of the neutropenia culture of bone marrow for granulocyte-macrophage colony forming cells (GMCFCs) was performed. Two cases had a low incidence of GMCFCs, but the third case had a high incidence. These...

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Suppressor cell-mediated neutropenia in Felty's syndrome.

The mechanism of neutropenia in Felty's Syndrome (FS) was tested. The suppressor capacity of mononuclear cells from patients with FS on normal bone marrow granulopoiesis was tested by the in vitro colony forming unit in culture assay. Peripheral blood, bone marrow, and spleen cells from FS patients with marked neutropenia (less than 1,000 neutrophils/mm3) suppressed the colony forming unit in c...

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Acute respiratory distress syndrome during neutropenia recovery

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ژورنال

عنوان ژورنال: BMJ

سال: 1957

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5053.1094